
Thermo Fisher Scientific RENT1 Polyclonal Antibody
Western blot과 Immunoprecipitation에 적합한 RENT1(UPF1) 폴리클로날 항체. Goat 유래 IgG로, 액상 형태이며 1 mg/mL 농도. 4°C 보관, 1년 안정성 보장. NMD 관련 단백질 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:10,000–1:25,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1075 and the C-terminus (residue 1118) of Human Regulator of Nonsense Transcripts 1 (UPF1, UniProt ID: Q92900-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
Upf1 is an active component in nonsense-mediated decay (NMD), an mRNA surveillance mechanism in eukaryotic cells that degrades mRNAs containing premature termination codons. It functions as an ATP-dependent RNA helicase in the cytoplasm and is also a component of cytoplasmic P-bodies. Upf1 phosphorylation mediates translation repression during NMD, facilitating mRNA accessibility to the decay machinery. Other NMD components include Upf2 and Upf3, which exhibit perinuclear and nucleocytoplasmic localization, respectively.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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