Thermo Fisher Scientific RENT1 Polyclonal Antibody
RENT1 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot 및 Immunoprecipitation에 적합. Human과 Mouse 반응성. 항원 친화 크로마토그래피로 정제된 액상 제품으로, 4°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:10,000–1:25,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1075 and the C-terminus (residue 1118) of Human Regulator of Nonsense Transcripts 1 (UPF1, UniProt ID: Q92900-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
Upf1 is an active component in nonsense-mediated decay (NMD), an mRNA surveillance mechanism in eukaryotic cells that degrades mRNAs containing premature termination codons.
It functions as an ATP-dependent RNA helicase in the cytoplasm and is a component of cytoplasmic P-bodies.
Upf1 phosphorylation mediates translation repression during NMD, facilitating mRNA accessibility to the NMD machinery.
Other NMD components, Upf2 and Upf3, exhibit perinuclear and nucleocytoplasmic localization, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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