Thermo Fisher Scientific Phospho-RRN3 (Ser649) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human RRN3(Accession Q9NYV6), corresponding to amino acid residues around phosphorylated Ser649. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RRN3,uniProtId:Q9NYV6-1,ncbiNodeId:9606,antigenRange:649,antigenLength:651,antigenImageFileName:PA5-103273_RRN3_Q9NYV6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103273_RRN3_Q9NYV6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2815972

Product Specific Information

Antibody detects endogenous levels of TIF1 alpha only when phosphorylated at Ser649.

Target Information

Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.