Thermo Fisher Scientific Phospho-OXSR1 (Thr185) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human OXSR1(Accession O95747), corresponding to amino acid residues around phosphorylated Thr185. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:OXSR1,uniProtId:O95747-1,ncbiNodeId:9606,antigenRange:185,antigenLength:527,antigenImageFileName:PA5-103272_OXSR1_O95747-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103272_OXSR1_O95747-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

sequential chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2815971

Product Specific Information

Antibody detects endogenous levels of OSR1 only when phosphorylated at Thr185.

Target Information

OXSR1 serine/threonine kinase or (OSR1) is activated by osmotic stresses and regulates downstream protein kinases such as PAK1 in order to establish the sensor/signaling modules that initiate the cellular response to environmental stress. OXSR1 can be phosphorylated by ATM or ATR during the DNA damage process. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.