Thermo Fisher Scientific Phospho-OXSR1 (Thr185) Polyclonal Antibody
Phospho-OXSR1 (Thr185) 특이적 폴리클로날 항체로 인간, 마우스, 랫트 시료에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 액상 형태로 PBS와 글리세롤에 보관됩니다. 세포 내 인산화된 OSR1 단백질 검출에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human OXSR1 (Accession O95747), corresponding to amino acid residues around phosphorylated Thr185 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2815971 |
Product Specific Information
This antibody detects endogenous levels of OSR1 only when phosphorylated at Thr185.
Target Information
OXSR1 serine/threonine kinase (OSR1) is activated by osmotic stress and regulates downstream protein kinases such as PAK1 to establish sensor/signaling modules that initiate cellular responses to environmental stress. OXSR1 can be phosphorylated by ATM or ATR during DNA damage processes and may play a role in regulating the actin cytoskeleton.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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