Thermo Fisher Scientific FAM3B Polyclonal Antibody
FAM3B 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. IHC(P) 및 ICC/IF에 사용 가능하며, 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 항체로, 26 kDa 내인성 단백질 검출에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length human FAM3B (amino acids 1–235, UniProt ID: P58499-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2554003 |
Product Specific Information
- Detects endogenous protein at a molecular weight of approximately 26 kDa.
- Purity is >95% by SDS-PAGE.
Target Information
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11, or PANDER, is a 235 amino acid secreted protein localized to vesicular and perinuclear structures. It is highly expressed in the pancreas and at lower levels in kidney, colon, testis, prostate, and small intestine. FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit insulin secretion from beta-cells, potentially influencing overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, indicating a conserved role across species. Three isoforms (A, B, and C) exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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