
Thermo Fisher Scientific BMP-7 Monoclonal Antibody (164311)
인간 BMP-7에 특이적인 Mouse IgG2b 단일클론 항체로, WB, IHC(P), 중화 실험 등에 사용 가능. ELISA에서 rhBMP-6과 약 25% 교차반응을 보이며 다른 BMP와는 교차반응 없음. Protein A/G 정제, PBS+trehalose 저장, 보존제 무첨가.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 8–25 µg/mL |
| Neutralization (Neu) | 1.5–6.0 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 164311 |
| Immunogen | CHO-derived recombinant human BMP-7 (Ser293–His431) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| RRID | AB_2609304 |
Product Specific Information
- In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) BMP-6 is observed.
- No cross-reactivity with rhBMP-2, -3, -4, -5, or -8.
- Endotoxin level: <0.10 EU per 1 µg of antibody (LAL method).
Target Information
Bone morphogenetic proteins (BMPs) are secreted signaling molecules capable of inducing ectopic bone growth. Many BMPs belong to the transforming growth factor-beta (TGF-β) superfamily. BMPs were first identified by their ability to induce endochondral osteogenesis from demineralized bone extracts. BMP-7, expressed early in embryogenesis, is implicated in developmental processes and may possess bone-inductive activity similar to BMP-5 and BMP-6.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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