Thermo Fisher Scientific VEGF Receptor 1 Polyclonal Antibody
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA137710 | - | Thermo Fisher Scientific PA137710 VEGF Receptor 1 Polyclonal Antibody 1 mL pk | 재고문의 | pk | 920,000원 | - | 1,012,000원 | |
PA532408 | - | Thermo Fisher Scientific PA532408 VEGF Receptor 1 Polyclonal Antibody 500 ul pk | 재고문의 | pk | 732,000원 | - | 805,200원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Immunohistochemistry (IHC)
-
View 1 publication 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
1:50
Immunocytochemistry (ICC/IF)
5 µg/mL
Miscellaneous PubMed (Misc)
-
View 1 publication 1 publication
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from C-terminus of human FLT-1. if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
VEGF Receptor 1,
uniProtId:
P17948-1,
ncbiNodeId:
9606,
antigenRange:
1338,
antigenLength:
1338,
antigenImageFileName:
PA1-37710_VEGF_Receptor_1_P17948-1_Rabbit.svg,
antigenImageFileNamePDP:
PA1-37710_VEGF_Receptor_1_P17948-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.4 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.6, with 1% BSA
Contains
0.1% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2107042
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is placenta or angiosarcoma.
Target Information
FLT1 (VEGFR1) is a receptor tyrosine kinase which plays a critical role in angiogenesis. Active angiogenesis has been found to play important role in many pathological and physiological processes, such as tumor progression, diabetic retinopathy, rheumatoid arthritis and wound healing. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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