Thermo Fisher Scientific IL9R alpha Monoclonal Antibody (AH9R7)
인간 IL9R 알파(CD129)에 특이적인 Mouse 단클론 항체로, Flow Cytometry 및 ELISA에 사용 가능. 비결합형(Unconjugated) 형태이며, Protein A로 정제됨. PBS 완충액에 보관하며 4°C에서 보존. 연구용으로만 사용.
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Applications
- Flow Cytometry (Flow): Assay-Dependent
- ELISA: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AH9R7 |
| Immunogen | Human CD129-transfected cell line |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745517 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells, and neurons.
Flow cytometry: It is recommended to use bright fluorochromes or signal multiplying detection.
Target Information
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor gamma (IL2RG) subunit, shared by many cytokine receptors. Ligand binding activates JAK kinases and STAT proteins, leading to various biological responses.
This gene is located in the pseudoautosomal regions of the X and Y chromosomes and has been associated with asthma development. Multiple pseudogenes exist on chromosomes 9, 10, 16, and 18. Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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