Thermo Fisher Scientific IL9R alpha Monoclonal Antibody (AH9R7), PE
IL9R alpha (CD129) 단백질을 인식하는 마우스 단클론 항체로, PE 형광 표지되어 있습니다. Flow Cytometry에 최적화되어 있으며, 사람 시료에 반응합니다. 면역원은 인간 CD129-transfected 세포주입니다. 연구용으로만 사용 가능합니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: 10 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | AH9R7 |
| Immunogen | Human CD129-transfected cell line |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745516 |
Additional Formats
Product Specific Information
This antibody recognizes an extracellular epitope of CD129 / IL-9R alpha, a 57 kDa type I transmembrane glycoprotein expressed at low levels by lymphocytes, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells, and neurons.
Recommended dilution is for 100 µL of whole blood or 1×10⁶ cells in suspension.
Target Information
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. Ligand binding of this receptor activates various JAK kinases and STAT proteins, leading to multiple biological responses.
This gene is located at the pseudoautosomal regions of X and Y chromosomes and has been associated with asthma development. Multiple pseudogenes exist on chromosomes 9, 10, 16, and 18. Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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