Thermo Fisher Scientific 53BP2 Polyclonal Antibody
53BP2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며 인간, 마우스, 랫트 시료에 반응. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, -20°C 보관.
- 카탈로그번호
- PA5105248
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific 53BP2 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TP53BP2 (Accession Q13625), corresponding to amino acid residues G672–R722 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853854 |
Product Specific Information
Antibody detects endogenous levels of total ASPP2.
Target Information
Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions.
Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.
Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, thereby decreasing APPBP1 ability to induce apoptosis.
Impede cell cycle progression at G2/M.
Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-105248_53BP2_Q13625-1_Rabbit.svg, PA5-105248_53BP2_Q13625-1_Rabbit_PDP.jpeg)
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