Thermo Fisher Scientific ING3 Polyclonal Antibody
ING3 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화됨. 인간에 반응하며, 마우스·랫·돼지·소에 예측 반응. 항원 친화 크로마토그래피로 정제, 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 84–179 of Human ING3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 40% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545193 |
Product Specific Information
- Recommended positive controls: H1299, HepG2
- Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that interacts with TP53, inhibits cell growth, and induces apoptosis. It contains a PHD-finger motif involved in chromatin remodeling. This gene can activate p53 trans-activated promoters such as p21/waf1 and bax. Overexpression inhibits cell growth and induces apoptosis. Allelic loss and reduced expression have been detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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