Thermo Fisher Scientific HSP90AB1 (Heat Shock Protein 90) Monoclonal Antibody (HSP90AB1, 3952)
Human HSP90AB1 단백질을 인식하는 Mouse monoclonal antibody로 WB, IHC, Peptide Array에 적합합니다. Recombinant human HSP90AB1(aa581-704)로 면역화되었으며, Protein A/G로 정제된 액상형 제품입니다. 세포 내 스트레스 반응 및 단백질 접힘 연구에 활용됩니다.
- 카탈로그번호
- 3326-MSM2-P0
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- pk
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1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific HSP90AB1 (Heat Shock Protein 90) Monoclonal Antibody (HSP90AB1, 3952)
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HSP90AB1, 3952 |
| Immunogen | Recombinant human HSP90AB1 protein fragment (around aa581–704) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Heat shock proteins (HSPs) are expressed in response to various biological stresses, including heat.
HSP90 is a 90 kDa protein induced under stress conditions and is one of the most abundant cellular proteins under non-stress conditions.
HSP90 proteins are highly conserved molecular chaperones involved in signal transduction, protein folding, degradation, and morphologic evolution.
They associate with cochaperones to assist in folding newly synthesized proteins or refolding denatured proteins after stress.
HSP90 interacts with intracellular proteins such as steroid receptors, actin, tubulin, aryl hydrocarbon receptor, and kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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