Thermo Fisher Scientific RFTN1 Polyclonal Antibody
RFTN1 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB 및 ICC/IF에 적합합니다. 인간과 마우스 반응성이 있으며, 고순도 affinity chromatography로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific RFTN1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RFTN1 (Accession Q14699), corresponding to amino acid residues R431–L481 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851240 |
Product Specific Information
Antibody detects endogenous levels of total RFTN1.
Target Information
Raftlin, also known as RFTN1 (raftlin, lipid raft linker 1), cell migration-inducing gene 2 protein, PIB10, PIG9 or MIG2, is a 578 amino acid cell membrane protein and lipid anchor essential for raft cell assembly and maintenance.
Raftlin modulates B-cell antigen receptor-mediated signaling and TCR signals, and is involved in T cell-mediated immune responses.
The gene encoding Raftlin maps to human chromosome 3, which contains over 1,100 genes, including a chemokine receptor (CKR) gene cluster and various cancer-related loci.
Key tumor suppressor genes on chromosome 3 include RASSF1 (apoptosis mediator), HYAL1 (cell migration regulator), and SEMA3B (angiogenesis suppressor).
Genetic diseases associated with chromosome 3 include Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta, and Charcot-Marie-Tooth Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-101808_RFTN1_Q14699-1_Rabbit.svg, PA5-101808_RFTN1_Q14699-1_Rabbit_PDP.jpeg)
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