Thermo Fisher Scientific CD45 Monoclonal Antibody (HI30), Alexa Fluor 700
인간 CD45 항원을 인식하는 Mouse IgG1 단클론 항체로, Alexa Fluor 700 형광체로 표지됨. Flow Cytometry에 적합하며, PBS/BSA 완충액에 보존. 696/719 nm 파장에서 높은 발광 효율을 보임. 4°C 암소 보관.
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Applications
- Flow Cytometry (Flow): Assay-Dependent
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HI30 |
| Immunogen | CD45 antigen |
| Conjugate | Alexa Fluor™ 700 |
| Excitation / Emission Max | 696 / 719 nm |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | PBS with 4 mg/mL BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10373857 |
Additional Available Formats
- Alexa Fluor 405
- Alexa Fluor 488
- APC
- APC-Alexa Fluor 750
- Biotin
- FITC
- Pacific Blue
- Pacific Orange
- PE
- PE-Alexa Fluor 610
- PE-Cyanine5.5
- PE-Cyanine7
- PE-Texas Red
- PerCP
- Qdot 605
- Qdot 655
- Qdot 800
- TRI-COLOR
- Request custom conjugation available
Product Specific Information
The Alexa Fluor™ 700 dye conjugate provides an excellent spectral match to common long-wavelength excitation sources and exhibits a high extinction coefficient, making it ideal for multicolor flow cytometry applications.
Target Information
CD45 (LCA, leukocyte common antigen) is a receptor-type protein tyrosine phosphatase (PTP) expressed in all nucleated hematopoietic cells, accounting for about 10% of lymphocyte surface proteins. It is absent in non-hematopoietic cells and tissues. CD45 plays a critical role in lymphocyte development and antigen signaling by regulating Src-family kinases. Multiple isoforms exist due to alternative splicing, differing mainly in extracellular domains. CD45 regulates T- and B-cell receptor signaling, modulates integrin-mediated pathways, and influences apoptosis and cytokine receptor signaling.
Analyte Specific Reagent
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