Thermo Fisher Scientific CD23 Monoclonal Antibody (D3.6), FITC
인간 CD23 항원을 인식하는 Mouse IgG2a 단클론 항체로 FITC 형광 표지. Flow Cytometry(FACS)용으로 최적화됨. Protein G 정제, PBS/BSA 버퍼, 0.09% sodium azide 포함. 4°C 단기 보관, -20°C 장기 보관 권장.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: Neat
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D3.6 |
| Immunogen | CD23 antigen from purified plasma membranes from EBV-transformed human lymphoblastoid B cell lines |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538136 |
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
Target Information
CD23 is a 45 kDa glycoprotein present on a subpopulation of freshly isolated peripheral blood and tonsil B cells and strongly expressed on EBV-transformed B lymphoblasts.
It is identical to the low-affinity IgE receptor found on B cells. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic lymphocytic leukemia and some cases of centroblastic/centrocytic lymphoma.
Functionally, CD23 is involved in B cell growth and differentiation, and IgE production. The soluble form acts as a potent mitogenic factor.
Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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