Thermo Fisher Scientific Cdc25C Polyclonal Antibody
Rabbit polyclonal antibody targeting human CDC25C, validated for WB and ICC/IF. High specificity and predicted cross-reactivity with chimpanzee. Supplied as a liquid, unconjugated form at 1 mg/mL. Ideal for studying cell cycle regulation and mitosis co...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human CDC25C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792649 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Chimpanzee (100%).
- Positive Control: Jurkat, Raji, K562, NCI-H929, HeLa (untreated), HeLa (100 ng/mL Nocodazole treatment for 24 hr), Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12, PC-12, Rat2.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
M-phase inducer phosphatase 3 is an enzyme encoded by the CDC25C gene in humans. This gene is highly conserved during evolution and plays a key role in regulating cell division. The encoded protein is a tyrosine phosphatase belonging to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants have been described, though the full-length nature of many remains unknown.
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm. For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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