
Thermo Fisher Scientific ATR Polyclonal Antibody
ATR 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, IP 등 다양한 응용에 적합. 인간 및 생쥐 반응성. 고순도 항원 친화 크로마토그래피 정제. 연구용 전용 제품.
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Thermo Fisher Scientific ATR Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:5,000 |
| Immunoprecipitation (IP) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ATR (UniProt ID: Q13535-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792647 |
Product Specific Information
- Keep as concentrated solution.
- Positive Control: 293T, A431, HeLa, HepG2, Raji, Raji NE, Raji nuclear extract.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The ATR protein is a serine/threonine kinase and DNA damage sensor that activates cell cycle checkpoint signaling upon DNA stress. It phosphorylates and activates proteins involved in DNA replication inhibition, mitotic regulation, and DNA repair. ATR plays a critical role in fragile site stability and centrosome duplication. Mutations in this gene are associated with Seckel syndrome 1.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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