Thermo Fisher Scientific ERAB Monoclonal Antibody (10D12)
인간 ERAB 단백질을 인식하는 단클론 항체로 Western blot, IHC(F), Dot blot 등에 사용 가능. 마우스 IgG2b 아이소타입, 비결합형 액상 형태. 1 mg/mL 농도로 제공되며 PBS 버퍼에 보존제 없음. Alzheimer 연구 등 ERAB 관련 연구용으로 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:1,000 | - |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:1,000 | - |
| Dot blot (DB) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10D12 |
| Immunogen | Recombinant, full-length Human ERAB protein (Fusion protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1957650 |
Product Specific Information
MA1-90441 detects ERAB from human samples.
Target Information
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily.
The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids.
The protein has been implicated in the development of Alzheimer’s disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD).
Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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