Thermo Fisher Scientific ASIC1 Monoclonal Antibody (N271/44), APC
ASIC1 단백질을 표적하는 마우스 단클론 항체로, APC로 결합되어 형광 검출에 적합합니다. Western blot, IHC, ICC/IF에 사용 가능하며, 인간, 마우스, 랫트 시료에 반응합니다. 단백질 G 정제, 1 mg/mL 농도, 4°C 보관.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ASIC1 Monoclonal Antibody (N271/44), APC
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N271/44 |
| Immunogen | Fusion protein amino acids 460–526 (Cytoplasmic C-terminus) of mouse ASIC1 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932046 |
Available Formats
- Unconjugated (MA5-27640)
- FITC (MA5-45593)
- PE (MA5-45595)
- PerCP (MA5-45594)
- Custom conjugation available upon request
Product Specific Information
- 1 µg/mL of MA5-45592 was sufficient for detection of ASIC1 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Detects approximately 60 kDa.
- This antibody was formerly sold as clone S271-44.
Target Information
ASIC1 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of this family are amiloride-sensitive sodium channels with intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop rich in cysteine residues with conserved spacing.
ASIC1 is expressed in most brain neurons and may function as a cation channel gated by extracellular protons and inhibited by amiloride. It is permeable to Ca²⁺, Li⁺, and K⁺, and is expressed in dorsal root ganglia, sciatic nerves, olfactory bulb, cortical regions, hippocampus, amygdala, cerebellum, and various basal ganglia regions. Isoform 3 is expressed only in dorsal root ganglion, while isoform 1 is expressed in DRG, spinal cord, trigeminal ganglia, and trigeminal mesencephalic nucleus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.