Thermo Fisher Scientific NMT2 Polyclonal Antibody
Thermo Fisher Scientific의 NMT2 Polyclonal Antibody는 인간 NMT2 단백질을 인식하는 고품질 토끼 다클론 항체입니다. Western blot, IHC, ICC/IF에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 단백질 분해 경로 및 세포 내 조절 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NMT2. Recombinant protein control fragment (Product #RP-95117). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644724 |
Product Specific Information
Immunogen sequence:
GGTKSDSASD SQEIKIQQPS KNPSVPMQKL QDIQRAMELL SACQGPARNI DEAAKHRYQF WDTQPVPKLD EVITSHGAIE PDKDNVRQEP YSLPQGFMWD TLDLSDAEVL KELYTLLNEN YVEDDDNMFR FDYSPEFLLW ALRPPGWLL
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 78%
Target Information
Proteolytic degradation is critical to maintaining appropriate levels of short-lived and regulatory proteins involved in metabolism, stress response, antigen presentation, receptor modulation, ion channel regulation, cell cycle, transcription, and signaling.
The ubiquitin-proteasome pathway deconstructs most proteins in the eukaryotic cytosol and nucleus, while others are degraded via the vacuolar pathway (endosomes, lysosomes, ER).
The 26S proteasome is an ATP-dependent, multisubunit (~31), barrel-shaped molecular machine (~2.5 MDa), consisting of a 20S core complex and 19S regulatory subunits.
Defects in this pathway are linked to diseases such as cystic fibrosis, Angelman’s syndrome, and Liddle syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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