Thermo Fisher Scientific PC4 Polyclonal Antibody
Human PC4 단백질을 인식하는 Rabbit 폴리클로날 항체로, Western blot, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 버퍼에 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PC4. Recombinant protein control fragment (Product #RP-95157). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.02 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645240 |
Product Specific Information
Immunogen sequence:
VSSSSSGSDS DSEVDKKLKR KKQVAPEKPV KKQKTGETSR ALSSSKQSSS SRDDNMFQIG KMRYVSVRDF KGKVLIDIRE YWMDPEGEMK PGRKGISLNP EQWSQLKEQI
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 93%
Target Information
PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator that can suppress promoter-driven and nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH, which protects promoters from PC4-mediated repression through ERCC3 helicase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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