Thermo Fisher Scientific MPST Polyclonal Antibody
Thermo Fisher Scientific의 MPST 폴리클로날 항체는 인간 MPST 단백질을 인식하며, Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었고, PBS 버퍼와 글리세롤로 안정화되어 있습니다. 연구용으로만 사용 가능합니다.
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- PA551548
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MPST. Recombinant protein control fragment (Product #RP-91349). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644090 |
Product Specific Information
Immunogen sequence:
AVSLLDGGLR HWLRQNLPLS SGKSQPAPAE FRAQLDPAFI KTYEDIKENL ESRRFQVVDS RATGRFRGTE PEPRDGIEPG HIPGTVNIPF TDFLSQEGLE KSPEEIRHLF QEKKVDLSKP LVATCGSGVT ACHVALGAYL CGKPD
Sequence identity with orthologs:
- Mouse: 81%
- Rat: 82%
Target Information
This protein catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification.
There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), a mitochondrial protein.
Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU).
Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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