Thermo Fisher Scientific RPL36/Ribosomal Protein L36 Polyclonal Antibody
RPL36 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 사람과 마우스에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 4°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:10,000–1:25,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 55 to 105 of Human 60S ribosomal protein L36 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- Based on 100% sequence identity, this antibody is predicted to react with Rat, X. laevis, X. tropicalis, Chicken, Bovine, and Orangutan.
Target Information
The exosome is involved in various cellular RNA processing and degradation events. DIS3 (exosome complex exonuclease RRP44) is a ribonuclease that participates in RNA processing, turnover, and surveillance of multiple RNA species. It localizes in both cytoplasm and nucleus, contains one PINc domain, and is widely expressed, with highest levels in testis. DIS3 is required for processing 7S pre-RNA into a mature nuclear complex and proper mitotic progression. Abnormal expression of DIS3 may be linked to colon cancer, suggesting a possible role in tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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