Thermo Fisher Scientific YARS/Tyrosyl-tRNA Synthetase/TYRRS Polyclonal Antibody
Rabbit polyclonal antibody targeting human Tyrosyl-tRNA synthetase (YARS). Validated for WB and IP applications. Unconjugated, liquid form with 1 mg/mL concentration. Predicted cross-reactivity with rat and orangutan. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of Human Tyrosyl-tRNA synthetase, cytoplasmic |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat and Orangutan
Target Information
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution.
Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts:
- N-terminal fragment: harbors the catalytic site and acts as an interleukin-8-like cytokine
- C-terminal fragment: found only in mammalian enzyme and functions as an EMAP II-like cytokine
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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