Thermo Fisher Scientific CDKN2B Monoclonal Antibody (OTI7C4), TrueMAB
CDKN2B 단백질을 인식하는 Mouse monoclonal antibody로, Western blot에 최적화됨. HEK293T 세포에서 발현된 full-length human CDKN2B를 면역원으로 사용. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7C4 |
| Immunogen | Full-length human recombinant protein of human CDKN2B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The four known INK4 proteins (p15INK4b, p16INK4a, p18INK4c, and p19INK4d) inhibit CDK4 and CDK6 but not other CDKs such as cyclin E-Cdk2, cyclin A-Cdk2, or cyclin B-Cdk1.
INK4 genes are expressed in distinct tissue-specific patterns, indicating non-redundant functions.
p18INK4c is expressed during G1 to S transition and is maximally induced as cells enter S-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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