Thermo Fisher Scientific LMTK3 Monoclonal Antibody (6C5)
LMTK3 단백질을 인식하는 Mouse 단일클론 항체로 Western blot 및 ELISA에 적합. Human 시료 반응성. Affinity chromatography로 정제된 액상 형태. -20°C에서 보관하며 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.03 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6C5 |
| Immunogen | LMTK3 (XP_055866, 1151–1250 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
VLVNGGLTPP KSEDKVSENG GLRFPRNTER PPETGPWRAP GPWEKTPESW GPAPTIGEPA PETSLERAPA PSAVVSSRNG GETAPGPLGP APKNGTLEPG
Target Information
Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation.
May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804).
Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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