Thermo Fisher Scientific LMTK3 Monoclonal Antibody (5A10)
Thermo Fisher Scientific의 LMTK3 단클론 항체(5A10)는 인간 LMTK3 단백질을 표적으로 하는 Mouse IgG1 항체로, Western blot 및 ELISA에 적합합니다. 액상 형태이며 방부제 없이 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- H00114783-M06A
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5A10 |
| Immunogen | LMTK3 (XP_055866, 1151–1250 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
VLVNGGLTPP KSEDKVSENG GLRFPRNTER PPETGPWRAP GPWEKTPESW GPAPTIGEPA PETSLERAPA PSAVVSSRNG GETAPGPLGP APKNGTLEPG
Target Information
Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation.
May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804).
Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: H00114783-M06A_LMTK3_Q96Q04-1_House_mouse.svg)
(이미지 파일: H00114783-M06A_LMTK3_Q96Q04-1_House_mouse_PDP.jpeg)
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