Thermo Fisher Scientific CD34 Monoclonal Antibody (4H11), APC, eBioscience
인간 CD34 항원을 인식하는 4H11 클론 단일클론 항체로, APC 형광 표지되어 흐름세포분석(Flow Cytometry)에 적합합니다. 혈액세포 및 줄기세포 표지용으로 사용되며, 고순도 친화크로마토그래피 정제 및 안정적 액상 형태로 제공됩니다.
- 카탈로그번호
- 17-0349-4x (2개 옵션)
- 판매단위
- pk
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Thermo Fisher Scientific CD34 Monoclonal Antibody (4H11), APC, eBioscience™
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.25 µg)/test
Publications: View 77 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4H11 |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2016604 |
Available Formats
- Unconjugated
- Alexa Fluor 700
- APC-eFluor 780
- Biotin
- eFluor 450
- FITC
- PE
- PE-Cyanine5
- PE-Cyanine7
- PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 600
- Super Bright 645
- Request custom conjugation
Product Specific Information
The 4H11 monoclonal antibody reacts with human CD34, also known as mucosialin. CD34 is a single-pass transmembrane glycoprotein expressed on hematopoietic progenitors and certain mesenchymal stem cells, tumor cell lines, and vascular endothelia.
The 4H11 antibody belongs to class III epitopes, reacting with a protein epitope.
Applications reported include flow cytometric analysis.
Pre-titrated for use at 5 µL (0.25 µg) per test (100 µL final volume).
Excitation: 633–647 nm; Emission: 660 nm; Laser: Red Laser.
Filtered at 0.2 µm post-manufacturing.
Target Information
CD34 is a highly glycosylated monomeric surface protein (111–115 kDa) expressed on various stem cell populations. It functions as a stem cell marker and may act as an adhesion molecule mediating attachment to bone marrow matrix or stromal cells.
CD34 expression correlates with specific hematopoietic developmental states, influencing adhesion, differentiation, and proliferation.
It may present carbohydrate ligands to selectins and is phosphorylated by activated protein kinase C, suggesting a role in signal transduction.
Diseases associated with CD34 dysfunction include dermatofibrosarcoma and neurofibroma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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