Thermo Fisher Scientific TIGIT Monoclonal Antibody (OTI7E5)
인간 TIGIT 단백질을 인식하는 Mouse IgG2b 단일클론 항체. Western blot 및 유세포분석에 적합. 동결건조 형태로 제공되며 PBS와 8% 트레할로스 완충액 포함. 고친화도 결합 특성으로 연구용 면역분석에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7E5 |
| Immunogen | Full length human recombinant protein of human TIGIT (NP_776160) produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
TIGIT binds with high affinity to the poliovirus receptor (PVR), leading to increased IL10 secretion and decreased IL12B secretion. It suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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