Thermo Fisher Scientific GluR2/GluR3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (IHC)

-

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Rat

Published species

Mouse, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to the C-terminal region of rat GRIA2/3 conjugated to KLH if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GluR2/GluR3,uniProtId:P19491-1,ncbiNodeId:10114,antigenRange:883,antigenLength:883,antigenImageFileName:PA1-4660_GluR2GluR3_P19491-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4660_GluR2GluR3_P19491-1_Rabbit_PDP.jpeg,sortOrder:3},{targetFamily:GluR2/GluR3,uniProtId:P19492-1,ncbiNodeId:10114,antigenRange:888,antigenLength:888,antigenImageFileName:PA1-4660_GluR2GluR3_P19492-1_Rabbit.svg,antigenImageFileNamePDP:PA1-4660_GluR2GluR3_P19492-1_Rabbit_PDP.jpeg,sortOrder:4}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2279303

Product Specific Information

This antibody is predicted to react with chicken, human, mouse and zebrafish based on 100% sequence homology.

This antibody is specific for the ~100 kDa GluR2/3 protein.

Target Information

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.