Thermo Fisher Scientific GluR2 Polyclonal Antibody
Thermo Fisher Scientific의 GluR2 Polyclonal Antibody는 rat GluR2 단백질을 인식하는 rabbit IgG 항체로, Western blot에 적합합니다. AMPA 수용체 연구에 활용되며, 높은 특이성과 순도를 제공합니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:1,000
- View 5 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acid residues specific to rat GluR2 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2113757 |
Product Specific Information
This antibody is predicted to react with chicken, human, mouse, non-human primate, and zebrafish based on 100% sequence homology.
It is specific for the ~100 kDa GluR2 protein.
Target Information
Glutamate-activated ion channels are divided into two classes:
- NMDA receptors (NMDAR) — sensitive to N-methyl-D-aspartate
- AMPA receptors (AMPAR) — activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid
AMPARs consist of four Glutamate Receptor Subunits (GluR1–4) that play key roles in excitatory neurotransmission in the brain.
The GluR2 subunit is thought to be critical for synaptic plasticity such as long-term depression (LTD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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