Thermo Fisher Scientific Serum Amyloid P/APCS Monoclonal Antibody (APCS, 3240)
인간 Serum Amyloid P(APCS) 단백질을 인식하는 Mouse IgG2b 단일클론 항체. 면역조직화학(IHC) 및 Peptide Array에 사용 가능. 고순도 Protein A/G 정제, 액상 형태로 제공. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | APCS, 3240 |
| Immunogen | Recombinant fragment of human APCS protein (around aa 143–223) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
The protein encoded by this gene is a glycoprotein belonging to the pentraxin family, characterized by a pentameric organization. These proteins share sequence homology, likely due to gene duplication. The encoded protein binds to pathological amyloid cross-beta fold proteins, suggesting a potential chaperone role. It may also regulate chromatin degradation and binds to apoptotic cells at an early stage, indicating involvement in apoptotic cell clearance in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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