Thermo Fisher Scientific Serum Amyloid P/APCS Monoclonal Antibody (APCS, 3240)
인간 Serum Amyloid P(APCS) 단백질을 표적으로 하는 Thermo Fisher Scientific의 마우스 단클론 항체. IHC 및 Peptide Array에 사용 가능하며, 고순도 Protein A/G 정제 방식. 4°C 보관, 연구용으로만 사용.
- 카탈로그번호
- 325-MSM1-P1
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | APCS, 3240 |
| Immunogen | Recombinant fragment of human APCS protein (around aa 143–223) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
The protein encoded by this gene is a glycoprotein belonging to the pentraxin family, characterized by a pentameric organization. These family members share high sequence homology, likely due to gene duplication.
The binding of this protein to amyloid cross-beta fold structures suggests a role as a chaperone. It may also regulate chromatin degradation.
Additionally, it binds to apoptotic cells at an early stage, indicating a possible function in handling apoptotic cells in vivo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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