Thermo Fisher Scientific Phospho-Btk (Tyr551) Recombinant Rabbit Monoclonal Antibody (BtkY551-G12), PE
인간 BTK Tyr551 인산화 부위에 특이적인 재조합 토끼 단일클론 항체. PE 형광표지로 유세포분석(Flow Cytometry)에 적합. 고순도 Protein A/G 정제, PBS+BSA 완충액, 4°C 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Phospho-Btk (Tyr551) Recombinant Rabbit Monoclonal Antibody (BtkY551-G12), PE
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BtkY551-G12 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Tyr551 of human phospho Btk |
| Conjugate | PE |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897055 |
Additional Formats
- Unconjugated (MA5-37120)
- APC (MA5-37123)
- Biotin (MA5-37213)
- FITC (MA5-37122)
- Request custom conjugation
Target Information
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. It interacts with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9, which are critical molecules in both innate and adaptive immunity. BTK also interacts with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting its role in lipopolysaccharide signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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