Thermo Fisher Scientific NALP1 Polyclonal Antibody
Thermo Fisher Scientific의 NALP1 Polyclonal Antibody는 인간 NALP1 단백질을 인식하는 토끼 다클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 PBS 용액 형태로 제공됩니다.
- 카탈로그번호
- PA520005
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–4 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to 13 amino acids near the carboxy terminus of human NALP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154346 |
Product Specific Information
- A suggested positive control is U937 cell lysate.
- PA5-20005 can be used with blocking peptide PEP-0308.
Target Information
NALP1 is a member of the Ced-4 family of apoptosis-related proteins. Members of this family contain a caspase recruitment domain (CARD) and are key mediators of programmed cell death. NALP1 includes an N-terminal pyrin-like motif involved in protein-protein interactions. It interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene induces apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified, though the biological significance of some remains uncertain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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