Thermo Fisher Scientific Heart Fatty Acid Binding Protein (H-FABP)/FABP3 Monoclonal Antibody (FABP3/3430)
Human FABP3 단백질을 인식하는 Mouse Monoclonal 항체로, IHC 및 Peptide Array 등 다양한 응용에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, 4°C에서 보관. 지방산 결합 단백질 연구 및 세포 손상 마커 분석에 활용.
- 카탈로그번호
- 2170-MSM1-P0
- 판매단위
- pk
카탈로그
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-dependent
- Immunohistochemistry (PFA fixed) (IHC (PFA)): 1–2 µg/mL
- Peptide Array (Array): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FABP3/3430 |
| Immunogen | Human recombinant FABP3 protein fragment (around aa1–127) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C, do not freeze |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Fatty acid binding proteins (FABP) are small (approximately 13–14 kDa) intracellular proteins with high tissue specificity. FABPs bind long-chain fatty acids and are abundant in various cell types, playing an important role in intracellular fatty acid utilization.
There are at least six distinct types of FABP, each showing specific tissue expression. Due to their small size, FABPs leak rapidly from damaged or dying cells, increasing serum levels. Liver FABP serves as a sensitive marker for liver cell damage both in vitro and in vivo.
Histologically, damaged tissues often show absence or low presence of FABP, aiding recognition of such areas. L-FABP is also a marker for rapid hepatocyte lysis in vitro, useful in toxicology assays and liver damage detection during and after transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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