Thermo Fisher Scientific CDK6 Recombinant Rabbit Monoclonal Antibody (ARC0224)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:100

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC0224

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 227-326 of human CDK6 (Q00534) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDK6,uniProtId:Q00534-1,ncbiNodeId:9606,antigenRange:227-326,antigenLength:326,antigenImageFileName:MA5-35046_CDK6_Q00534-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35046_CDK6_Q00534-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2848951

Product Specific Information

Immunogen sequence: QLGKILDVIG LPGEEDWPRD VALPRQAFHS KSAQPIEKFV TDIDELGKDL LLKCLTFNPA KRISAYSALS HPYFQDLERC KENLDSHLPP SQNTSELNTA

Target Information

CDK6 functions as a cell-cycle initiator protein. This protein is coexpressed and copurified with CyclinD1. They are critical regulators of cell cycle progression. The prototype member of this family, p34cdc2, and a related protein cdk2, function late in the cycle while cdk4 and cdk6 are critically involved in G1 to S progression. CDK6 is essential for cell proliferation within the dentate gyrus of the hippocampus and the cuventricular zone of the lateral ventricles. Mutations in the gene results in microcephaly 12, primary, autosomal recessive (MCPH12).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.