Thermo Fisher Scientific CD49a Monoclonal Antibody (CL7207)
CD49a (Integrin α1) 단백질을 인식하는 Mouse IgG1 단일클론 항체로, WB 및 IHC(P) 실험에 적합. 인간 시료 반응성, Protein A 정제, PBS/glycerol buffer 보존. 세포 부착 및 MSC 조절 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL7207 |
| Immunogen | Synthetic Peptide corresponding to Human CD49a (Integrin alpha 1), UniProt ID: P56199-1, Antigen Range: 730–748 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2848946 |
Product Specific Information
Immunogen sequence: RQISRSFFSG TQERKVQRN
Target Information
Integrin alpha 1 (ITGA1) associates with beta 1 (ITGB1) to form a heterodimer functioning as a dual laminin/collagen receptor in neural and hematopoietic cells.
ITGA1 includes a 206-amino acid I domain, three divalent cation-binding sites, a transmembrane domain, and a short cytoplasmic tail.
It has 28 potential N-glycosylation sites and is expressed as a 180-kD protein in mouse fibroblast cells.
ITGA1 is involved in osteoarthritic cartilage remodeling and regulates mesenchymal stem cell proliferation and cartilage production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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