Thermo Fisher Scientific DWORF Polyclonal Antibody, FITC
DWORF 단백질을 인식하는 FITC 결합 토끼 폴리클로날 항체. Western blot, ELISA, IP 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 액상 형태로 제공되며 -20°C에서 어둡게 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to full-length Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF protein |
| Conjugate | FITC (Fluorescein) |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Enhances the activity of ATP2A1/SERCA1 ATPase in the sarcoplasmic reticulum by displacing ATP2A1/SERCA1 inhibitors, acting as a key regulator of skeletal muscle activity (PubMed:26816378, PubMed:30299255).
Does not directly stimulate SERCA pump activity (PubMed:26816378).
Enhances sarcoplasmic reticulum Ca²⁺ uptake and myocyte contractility by displacing the SERCA inhibitory peptides sarcolipin (SLN), phospholamban (PLN), and myoregulin (MRLN) (PubMed:26816378, PubMed:30299255).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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