Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT14/6987R)
인체 반응성 Recombinant Rabbit Monoclonal Antibody로서 KRT14 단백질을 인식합니다. 상피세포 및 편평세포암 마커로 활용 가능하며, IHC(P)와 IHC(PFA) 실험에 적합합니다. 단백질 A/G로 정제된 액상 제품으로, -20°C에서 보관합니다.
- 카탈로그번호
- 3861RBM27P1ABX
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Cytokeratin 14 (KRT14) (Squamous Cell Marker) Recombinant Rabbit Monoclonal Antibody (KRT14/6987R)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | KRT14/6987R |
| Immunogen | Recombinant human KRT14 fragment (around aa350–472) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Cytokeratins (CK) are intermediate filaments found in epithelial cells, both keratinizing (e.g., skin) and non-keratinizing (e.g., mesothelial cells). There are at least 20 different CKs identified. Most CKs are classified as either type I (acidic polypeptides) or type II (basic polypeptides).
Keratin 14 belongs to the type I subfamily of low molecular weight keratins and is typically expressed with keratin 5. It helps distinguish stratified epithelial cells from simple epithelial cells and is useful in identifying squamous cell carcinomas. Additionally, keratin 14 is considered a prognostic marker in breast carcinomas.
At least one acidic and one basic keratin are expressed in all epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: 3861-RBM27-P1ABX_Cytokeratin_14_P02533-1_Rabbit.svg, 3861-RBM27-P1ABX_Cytokeratin_14_P02533-1_Rabbit_PDP.jpeg)
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