Thermo Fisher Scientific Phospho-eIF2 beta (Tyr298) Polyclonal Antibody
Phospho-eIF2 beta (Tyr298) 항체로 인산화된 EIF2S2 단백질을 특이적으로 검출. Western blot 및 IHC(Paraffin)에 적합. Rabbit Polyclonal 형식으로 높은 특이성과 재현성 제공. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human EIF2S2 (Accession P20042), corresponding to amino acid residues around phosphorylated Tyr298 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816952 |
Product Specific Information
Antibody detects endogenous levels of EIF2S2 only when phosphorylated at Tyr298.
Target Information
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits—alpha, beta, and gamma—with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, recycling the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-105524_eIF2_beta_P20042-1_Rabbit.svg, PA5-105524_eIF2_beta_P20042-1_Rabbit_PDP.jpeg)
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