Thermo Fisher Scientific VEGF Receptor 2 Polyclonal Antibody
VEGF Receptor 2에 특이적인 Rabbit Polyclonal Antibody로, Human 및 Mouse 시료에 반응합니다. Western blot과 Immunocytochemistry에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 TBS 버퍼에 0.05% sodium azide 포함, 4°C 보관.
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- PA116613
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:250–1:1,000
- View 1 publication
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from internal region of murine VEGFR2 (residues 1200–1300) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_568766 |
Product Specific Information
- Target sequence shows 100% homology with mouse and rat.
- Suggested positive control: HUVEC lysate, antigen standard for KDR (transient overexpression lysate).
Target Information
KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase that binds vascular endothelial growth factor with high affinity. It is expressed early in development by endothelial cell precursors.
FLK1 (VEGF Receptor 2) encodes one of the two receptors for VEGF, known as kinase insert domain receptor.
The receptor’s signaling and trafficking are regulated by Rab GTPase, P2Y purine nucleotide receptor, integrin αVβ3, and T-cell protein tyrosine phosphatase.
Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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