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Thermo Fisher Scientific VAMP A/B Polyclonal Antibody
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Thermo Fisher Scientific VAMP A/B Polyclonal Antibody

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Rabbit polyclonal antibody recognizing VAMP A and B proteins. Suitable for WB and IHC in human, mouse, and rat samples. Lyophilized form, reconstitutable in sterile water. For research use only.

카탈로그번호
OSV00015G-500UG
판매단위
pk
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마지막 업데이트 2025. 07. 30. 오전 06:55
Thermo Fisher Scientific OSV00015G-500UG VAMP A/B Polyclonal Antibody 500 ug pk판매 단위 pk ·
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723,400원VAT 포함 795,740원

Thermo Fisher Scientific · Thermo Fisher Scientific VAMP A/B Polyclonal Antibody

Applications

Application Tested Dilution Publications
Western Blot (WB) 10–50 µg/mL -
Immunohistochemistry (IHC) 10–50 µg/mL -
Miscellaneous PubMed (Misc) - View 1 publication

Product Specifications

Specification Description
Species Reactivity Human, Mouse, Rat
Published Species Not Applicable
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen A synthetic peptide from aa region 50–100 of human VAMPB conjugated to an immunogenic carrier protein. Target family: VAPA/VAPB (UniProt ID: O95292-1, NCBI Node ID: 9606). Antigen range: 50–100.
Conjugate Unconjugated
Form Lyophilized
Concentration Not determined
Purification Ammonium sulfate precipitation
Storage Buffer PBS
Contains No preservative
Storage Conditions Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Reconstitute in 500 µL of sterile water.
  • Centrifuge to remove any insoluble material.
  • The peptide is homologous in many species including human, rat, mouse, zebrafish, bovine, xenopus, and chicken.
  • Specificity: VAMP A and B.

Target Information

VAPA/VAPB may play a role in vesicle trafficking. Present in the plasma membrane and intracellular vesicles. Interacts with VAMP1 and VAMP2.

Subunit: Homodimer and heterodimer with VAPA.
Subcellular Location: Cell membrane; Single-pass type IV membrane protein. Intracytoplasmic membrane; Single-pass type IV membrane protein.
Tissue Specificity: Ubiquitous. Isoform 1 predominates.

Disease Associations:

  • Defects in VAPB cause amyotrophic lateral sclerosis type 8 (ALS8), a familial neurodegenerative disorder affecting motor neurons.
  • Also associated with proximal adult autosomal dominant spinal muscular atrophy (late-onset Finkel type).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.


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