Thermo Fisher Scientific MSF (SEPT9) Monoclonal Antibody (OTI13B1)

Applications

• Western Blot (WB): 1:500–1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).

Target Information

The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB, Nrl) and small Mafs (MafF, MafK, MafG). Both contain leucine zipper motifs enabling homo- and heterodimerization with other bZip transcription factors.
Large Mafs possess an acidic transactivation domain, while small Mafs lack it but can act as transcriptional regulators by interacting with various partners.
Human MafF encodes a 164 amino acid protein with an extended leucine zipper structure and no N-terminal transactivation domain.
Small Maf proteins are involved in development, differentiation, hematopoiesis, and stress response through distinct mechanisms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.