Thermo Fisher Scientific Phospho-GLI3 (Ser664) Polyclonal Antibody
Phospho-GLI3 (Ser664) Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 GLI3의 Ser664 인산화 형태를 특이적으로 검출합니다. Western blot과 IHC(P) 응용에 적합하며, 고순도 정제 및 안정한 PBS/glycerol 버퍼로 제공됩니다. 연구용 전용 제품입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GLI3 (Accession P10071), corresponding to amino acid residues around phosphorylated Ser664 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817135 |
Product Specific Information
Antibody detects endogenous levels of Gli3 only when phosphorylated at Ser664.
Target Information
This gene encodes a protein belonging to the C2H2-type zinc finger proteins subclass of the Gli family. These proteins act as DNA-binding transcription factors and are key mediators of Sonic hedgehog (Shh) signaling. The encoded protein localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It plays a role during embryogenesis, and mutations are associated with Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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