Thermo Fisher Scientific MPP1 Polyclonal Antibody

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 0.25–2 µg/mL

Product Specifications

Product Specific Information

Immunogen sequence:
TEEMTRNISAN EFLEFGSYQG NMFGTKFETV HQIHKQNKIA ILDIEPQTLK IVRTAELSPF IVFIAPTDQG TQTEALQQLQ KDSEAIRSQY AHYFDLSLVN NGVDETLKKL QEAFDQACSS

• Highest antigen sequence identity to the following orthologs:
  • Mouse: 97%
  • Rat: 51%

Target Information

This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions.
The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain.
This gene product interacts with various cytoskeletal and junctional proteins in different tissues and cell types, and may be involved in regulating cell shape, hair cell development, neural patterning of the retina, and tumor suppression pathways in non-erythroid cells.
Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.