Thermo Fisher Scientific KV4.1 (KCND1) Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human KCND1. Recombinant protein control fragment (Product #RP-91925). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KV4.1 (KCND1),uniProtId:Q9NSA2-1,ncbiNodeId:9606,antigenRange:56-155,antigenLength:647,antigenImageFileName:PA5-64866_KV4.1_KCND1_Q9NSA2-1_Rabbit.svg,antigenImageFileNamePDP:PA5-64866_KV4.1_KCND1_Q9NSA2-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2664917

Product Specific Information

Immunogen sequence: NTLDRYPDTLL GSSEKEFFYD ADSGEYFFDR DPDMFRHVLN FYRTGRLHCP RQECIQAFDE ELAFYGLVPE LVGDCCLEEY RDRKKENAER LAEDEEAEQ

Highest antigen sequence identity to the following orthologs - mouse 99%, rat 99%.

Target Information

The KV gene family encodes more than 30 genes that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming alpha-subunits (KV alpha), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV beta subunits that modify the gating properties of the coexpressed KV alpha subunits. Differences exist in the patterns of trafficking, biosynthetic processing and surface expression of the major KV1 subunits (KV1. 1, KV1. 2 and KV1. 4) expressed in rat and human brain, suggesting that the individual protein subunits are highly regulated to control for the assembly and formation of functional neuronal channels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.