Thermo Fisher Scientific DNM1L Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 610-736 of human DRP1 (NP_0361922) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DNM1L,uniProtId:O00429-1,ncbiNodeId:9606,antigenRange:610-736,antigenLength:736,antigenImageFileName:PA5-87472_DNM1L_O00429-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87472_DNM1L_O00429-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.64 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804178

Product Specific Information

Positive Samples: PC-12; Cellular Location: Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Golgi apparatus, Membrane, Mitochondrion outer membrane, Peripheral membrane protein, Peroxisome, clathrin-coated pit, cytosol, secretory vesicle, synaptic vesicle membrane

Immunogen sequence: IPIMPASPQK GHAVNLLDVP VPVARKLSAR EQRDCEVIER LIKSYFLIVR KNIQDSVPKA VMHFLVNHVK DTLQSELVGQ LYKSSLLDDL LTESEDMAQR RKEAADMLKA LQGASQIIAE IRETHLW

Target Information

A human dynamin-related protein, DRP1 contributes to mitochondrial division in mammalian cells. It plays this important role in mitochondrial fission at steady state and during apoptosis. DRP1 is required for proper cellular distribution of mitochondria, and in mutant neurons, mitochondria are largely absent from synapses, thus providing a genetic tool to assess the role of mitochondria at synapses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.