Thermo Fisher Scientific DcR3 Polyclonal Antibody
Thermo Fisher Scientific DcR3 Polyclonal Antibody는 인간 및 랫트 시료에 반응하는 Rabbit IgG 기반 항체로, Western blot 및 ELISA에 적합합니다. 재조합 단백질 면역원으로 제작되었으며, 고순도 친화 크로마토그래피 정제 및 안정적인 PBS/glycerol 버퍼로 제공됩니다.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 200–300 of human TNFRSF6B (NP_003814.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.19 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804177 |
Product Specific Information
Immunogen sequence:
PLSTRVPGAE ECERAVIDFV AFQDISIKRL QRLLQALEAP EGWGPTPRAG RAALQLKLRR RLTELLGAQD GALLVRLLQA LRVARMPGLE RSVRERFLPV H
Positive Samples: HT-29
Target Information
Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by cytokines such as TNF and Fas ligand through their death domain-containing receptors, TNFR1 and Fas. Cell death signals are transduced by DD-containing adapter molecules and members of the ICE/CED-3 protease family. Daxx (death associated protein 6) binds specifically to the Fas death domain, enhances Fas-induced apoptosis, and activates the JNK pathway. Daxx is widely expressed in fetal and adult tissues, indicating its important role in Fas signaling pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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