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Thermo Fisher Scientific SPHK1 Polyclonal Antibody
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SPHK1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. 인간 SPHK1(AA 50-384) 서열 기반 면역원 사용. 세포막, 세포질, 핵에서 검출 가능하며, 암 연구 및 S1P 신호전달 관련 연구에 활용됩니다.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 04. 오후 10:21
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Thermo Fisher Scientific PA587473 SPHK1 Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
700,400원VAT 포함 770,440원
Thermo Fisher Scientific · Thermo Fisher Scientific SPHK1 Polyclonal Antibody
Thermo Fisher Scientific SPHK1 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 50–384 of human SPHK1 (NP_001136074.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.37 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804179 |
Product Specific Information
- Immunogen Sequence:
TLMLTERRNH ARELVRSEEL GRWDALVVMS GDGLMHEVVN GLMERPDWET AIQKPLCSLP AGSGNALAAS LNHYAGYEQV TNEDLLTNCT LLLCRRLLSP MNLLSLHTAS GLRLFSVLSL AWGFIADVDL ESEKYRRLGE MRFTLGTFLR LAALRTYRGR LAYLPVGRVG SKTPASPVVV QQGPVDAHLV PLEEPVPSHW TVVPDEDFVL VLALLHSHLG SEMFAAPMGR CAAGVMHLFY VRAGVSRAML LRLFLAMEKG RHMEYECPYL VYVPVVAFRL EPKDGKGVFA VDGELMVSEA VQGQVHPNYF WMVSGCVEPP PSWKPQQMPP PEEPL - Positive Samples: HeLa, Mouse kidney
- Cellular Location: Cell membrane, Cytoplasm, Nucleus
Target Information
SPHK1, along with SPHK2, catalyzes the phosphorylation of sphingosine to produce sphingosine-1-phosphate (S1P), a crucial signaling molecule. S1P regulates diverse cellular processes via G-protein coupled receptors. SPHK1 activity is associated with cell differentiation, calcium mobilization, and apoptosis. Inhibitors of SPHKs are potential cancer therapeutics.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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